Grand Theft Auto: San Andreas - Lutris

Play all your games on Linux. Lutris is an Open Source gaming platform for Linux. It installs and launches games so you can start playing without the hassle of setting up your game. Get your games from GOG, Steam, Battle.net, Origin, Uplay and many other sources running on any Linux powered gaming machine.

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A friend of mine just posted this on his Discord server: It's GTA: San Andreas via DXVK 2.1 running on NVK, at almost 60FPS. (He got it from the Linux Gaming Dev